Image for Chelation May Lower Risk of Heart Complications
Copyright 2013 Natural Standard (
November 2012

Chelation May Lower Risk of Heart Complications

New research suggests that chelation therapy may prevent other heart conditions in individuals with a previous heart attack.

Chelation generally refers to the use of any chemical in the blood to remove specific contaminants or toxins. Ethylenediaminetetraacetic acid (EDTA) is the most common substance used for chelation. EDTA chelation was first used in the 1940s for lead poisoning. There is theoretical rationale for EDTA chelation with cardiovascular disease, namely by the removal of calcium from the cardiovascular tissues and plaque. However, there is insufficient data to support this use.

The recent study enrolled 1708 individuals with a history of heart attack. Most participants were obese, had high blood pressure and high cholesterol. Participants were divided into an experimental group and a control group. The experimental group received 500 milliliters of a chelation solution intravenously, consisting of EDTA, vitamin B and vitamin C. The control group received 500 milliliters of a placebo solution intravenously, consisting of salt and sugar. Both groups received the intravenous solution 40 times.

Compared to the control group, the chelation group had fewer cardiovascular events, which included heart attack, stroke, coronary revascularization, hospitalization and death. Patients with diabetes showed a greater reduction in cardiovascular events from chelation therapy. Further research on this topic is still warranted.

For more information on chelation therapy, please visit Natural Standard's Health & Wellness Database


  1. Natural Standard: The Authority on Integrative Medicine.
  2. The American Heart Association.
The information in this brief report is intended for informational purposes only, and is meant to help users better understand health concerns. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions. Copyright 2013 Natural Standard Inc. Commercial distribution or reproduction prohibited.