Image for Pomegranate ()
Pomegranate (Punica granatum)

Synonyms/Common Names/Related Substances:

  • Aldehydes, anthocyanins, apigenin, ascorbic acid, ash, beta-sitosterol, beta-sitosterol esters, calcium, catechins, cellulose, citric acid, coemestrol, compound 25, copper, coumestrol, cyanidins, cycloartenol, daucosterol, delphinidins, ellagic acid, ellagitannins, estrone, fatty acids, flavonols, gallic acid, gallotannins, Granada, granatin B, Grenade, Grenadier, humarain, hydroalcoholic extract (HAE), iron, isopelletierine, isoquerecitrin, leucoanthocyanins, luteolin, magnesium, mannitol, methylgallate, minerals, monoterpenes, oleanolic acid, pectin, pelargonidins, pelletierine, phenolic acids, phosphorus, PJ, policosanol, polyphenols, pomegranate extracts, pomegranin, POMx™, potassium, pulicalagin, Punica granatum, Punica proto-punica, Punicaceae, punicalagins, punicalin, punicanolic acid, punicic acid, qualene, quinic acid, Shi liu gen (Chinese), Shi liu gen pi (Chinese), Shi liu pi (Chinese), sodium, sugar alcohols, sugars, tannins, tartaric acid, tocopherols, ursolic acid, vitamin B, vitamin C, zinc.
  • Combination product examples: Lakewood Organic Pure Pomegranate® (pomegranate juice), Odwalla Pomagrand® (pomegranate juice), POM Wonderful® (pomegranate juice), Pomeratrol™, Radical Fruit® (combination fruit supplement containing pomegranate juice), Swanson Ultra® (pomegranate juice), Weleda® Pomegranate Regenerating Body Care, emerginC® Pomegranate Gel Cleanser, Klorane® No Rinse Care With Pomegranate (conditioner), Radical Fruits®, Xanthigen® (brown marine algae fucoxanthin and pomegranate seed oil (PSO)).

Clinical Bottom Line/Effectiveness

Brief Background:

  • Pomegranate (Punica granatum L.) is cultivated around the world. It can be found throughout the Mediterranean region, Southeast Asia, and California and Arizona in the United States, and as far north as the Himalayas (1). One pomegranate delivers approximately 40% of an adult's daily vitamin C requirement and is high in polyphenol compounds. These compounds are thought to reduce "silent inflammation," which research has suggested is at the root of diseases such as cancer, heart disease, and diabetes.
  • Although pomegranate juice has been commonly consumed for atherosclerosis, evidence of its effectiveness is inconclusive. Preliminary research also suggests that pomegranate may be beneficial as an antioxidant and as a treatment for atherosclerosis, erectile dysfunction, high cholesterol, and prostate cancer. However, more information is required in these areas before a conclusion can be made.
  • Pomegranate has a long history of use as food and medicine in Asia and South America. In the United States, pomegranate is typically juiced or the seeds are used as food. Pomegranate may have medicinal use as an anthelmintic and antidiarrheal agent, although reports are conflicting. Several sources note that the fruit rind of pomegranate is actually contraindicated in those with diarrhea (2;3;4). The seeds may have phytoestrogenic qualities and may be used in hormone-related conditions, such as menopause.

Dosing/Toxicology

  • Content available for subscribers only.

Precautions/Contraindications

  • Content available for subscribers only.

Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

  • Content available for subscribers only.

Mechanism of Action

  • Content available for subscribers only.

History

  • Content available for subscribers only.

Evidence Table

  • Content available for subscribers only.

Evidence Discussion

  • Content available for subscribers only.

Products Studied

  • Content available for subscribers only.

Author Information

  • Content available for subscribers only.

References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

  • Content available for subscribers only.
The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.