Image for Duchenne muscular dystrophy
Duchenne muscular dystrophy

Related Terms

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Background

  • Duchenne muscular dystrophy (DMD) is an inherited genetic condition that affects about two out of every 10,000 people. Due to the inheritance pattern of DMD, males are more frequently affected with the disease than females (about 1 in 3,500 males is affected with DMD). DMD is part of a group of hereditary muscle diseases called muscular dystrophies.
  • Patients with DMD experience a progressive degeneration of muscle function beginning in infancy or early childhood. The loss of muscle function usually starts in the pelvis and the legs and eventually spreads to all parts of the body. Patients with DMD first lose the ability to walk, and eventually they lose the ability to move other parts of their bodies, such as the arms.
  • DMD is caused by a defect, or mutation, in a gene that contains instructions for making dystrophin, a protein that normally helps to maintain the structure and function of muscle. Individuals with DMD have reduced levels of this protein, so the muscles cannot carry out normal functions. Becker muscular dystrophy is another type of muscular dystrophy that is caused by a different type of mutation in the dystrophin gene.
  • Many patients with DMD eventually experience heart and/or lung complications, due to deterioration of muscles in these organs. This may lead to an inability to pump blood or breathe normally.
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Risk Factors

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Causes

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Signs and Symptoms

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Diagnosis

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Complications

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Treatment

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Integrative Therapies

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Prevention

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.