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Duane syndrome

Related Terms

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Background

  • Duane syndrome is a congenital condition that affects the eye muscles, making it difficult for a person to move his/her eyes. Normally, the outward wall of each eye is attached to six different muscles. These muscles are attached (wired) to nerves, and the brain controls eye movements by sending messages to the eye muscles through these nerves. In patients with Duane syndrome, the nerves are not properly attached to one or more of the eye muscles, so the brain cannot fully control movement of the eye.
  • Patients may have difficultly moving one or both eyes inwards (closer to the nose) or outwards (toward the ear). Some patients with Duane syndrome may exhibit strabismus, which is a misalignment of the eyes that causes the eyes to always appear to be pointing in different directions. Also, some patients may experience ambylopia (or lazy eye), which is poor or indistinct vision in the affected eye.
  • Miswiring of the eye muscles is thought to occur during embryonic development. Therefore, patients with Duane syndrome are born with the condition and usually exhibit symptoms soon after birth. For unknown reasons, the left eye appears to be affected more frequently than the right eye in patients with Duane syndrome. In 20% of Duane syndrome cases, the movement of both eyes is affected.
  • In some cases, medical problems not related to vision may occur in patients with Duane syndrome. These include loss of hearing, improper development of the vertebrae or spine, Goldenhaar syndrome (a defect involving developmental deformities of the face), or Holt-Oram syndrome (an abnormality of the upper limbs and heart).
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Risk Factors

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Causes

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Signs and Symptoms

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Diagnosis

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Complications

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Treatment

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Integrative Therapies

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Prevention

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.